Intraarticular use of tranexamic acid during primary total knee arthroplasty

Background: Tranexamic acid (TXA) is effective in reduction of blood loss after major surgical procedures. In TKA surgeries, it commonly administered intravenously. Since there are contraindications systemic use TXA, local/intraarticular TXA can also be used. The efficacy both and local administration demonstrated the literature. aim was to assess effect intraarticular during total knee arthroplasty terms transfusion rate. Methods: A 50 34 patients were included this prospective study. Patients received one dose 3 g skin closure before deflation tourniquet. Results: mean intra-articular 456.9 ml. None required postoperatively including those who underwent bilateral staged TKR. Mean postoperative hemoglobin 1.07. Conclusions: reduced requirement. Intra-articular seems more reducing rates. We recommend topical primary healthy decrease perioperative loss.